SIB-1757
产品说明书
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同义名 : | - |
| CAS号 : | 31993-01-8 | |
| 货号 : | A658258 | |
| 分子式 : | C12H11N3O | |
| 纯度 : | 99% | |
| 分子量 : | 213.24 | |
| MDL号 : | MFCD00506102 | |
| 存储条件： |
Pure form Keep in dark place, sealed in dry, room temperature In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | SIB-1757 is a highly selective, non-competitive mGlu5 receptor antagonist with an IC50 value of 0.4 μM [1].At a concentration of 2 μM, SIB-1757 reduces 3,5-DHPG-induced membrane depolarisation in neurons recorded from striatal cholinergic interneurons [2] | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
4.69mL 0.94mL 0.47mL |
23.45mL 4.69mL 2.34mL |
46.90mL 9.38mL 4.69mL |
