MAK683
产品说明书
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同义名 : | EED inhibitor-1 |
| CAS号 : | 1951408-58-4 | |
| 货号 : | A646657 | |
| 分子式 : | C20H17FN6O | |
| 纯度 : | 99% | |
| 分子量 : | 376.39 | |
| MDL号 : | MFCD31630846 | |
| 存储条件： |
Pure form Keep in dark place, sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | An inhibitor of embryonic ectoderm development protein (EED) and allosteric inhibitor of polycomb repressive complex 2 (PRC2), with potential antineoplastic activity. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02900651 | Diffuse Large B-cell Lymphoma | Phase 1 Phase 2 | Recruiting | August 5, 2019 | United States, California ... 展开 >> Novartis Investigative Site Recruiting San Francisco, California, United States, 94115 Novartis Investigative Site Recruiting Santa Monica, California, United States, 90404 Contact: Ruth M. Gonzalez Rngonzalez@mednet.ucla.edu Principal Investigator: Zev A. Wainberg United States, Texas Novartis Investigative Site Recruiting Houston, Texas, United States, 77030 Contact: Anna Lui 713-563-4667 alui@mdanderson.org Principal Investigator: Vivek Subbiah Canada, Ontario Novartis Investigative Site Recruiting Toronto, Ontario, Canada, M5G 2M9 France Novartis Investigative Site Recruiting Villejuif Cedex, France, 94805 Germany Novartis Investigative Site Recruiting Koeln, Germany, 50937 Hong Kong Novartis Investigative Site Recruiting Hong Kong, Hong Kong Italy Novartis Investigative Site Recruiting Milano, MI, Italy, 20133 Japan Novartis Investigative Site Recruiting Sunto-gun, Shizuoka, Japan, 411-8777 Singapore Novartis Investigative Site Recruiting Singapore, Singapore, 169610 Spain Novartis Investigative Site Recruiting Madrid, Spain, 28041 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.66mL 0.53mL 0.27mL |
13.28mL 2.66mL 1.33mL |
26.57mL 5.31mL 2.66mL |
| 参考文献 |
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