Glaucocalyxin B

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Chemical Structure| 80508-81-2 同义名 : 蓝萼乙素 B
CAS号 : 80508-81-2
货号 : A638683
分子式 : C22H30O5
纯度 : 99+%
分子量 : 374.47
MDL号 : MFCD28144511
存储条件:

Pure form

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Glaucocalyxin B is an ent kaurane diterpenoid isolated from the Chinese traditional medicine Rabdosia japonica with anticancer and antitumor activity and decreases the growth of HL-60 cells with an IC50 of approximately 5.86 μM at 24 h.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.67mL

0.53mL

0.27mL

13.35mL

2.67mL

1.34mL

26.70mL

5.34mL

2.67mL

参考文献

[1]Pan Y, Bai J, et al. Glaucocalyxin B induces apoptosis and autophagy in human cervical cancer cells. Mol Med Rep. 2016 Aug;14(2):1751-5.

[2]Yang WH, Zhang Z, et al. Glaucocalyxin A and B-induced cell death is related to GSH perturbation in human leukemia HL-60 cells. Anticancer Agents Med Chem. 2013 Oct;13(8):1280-90.