DUB-IN-3

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Chemical Structure| 924296-17-3 同义名 : Dubs-in-3
CAS号 : 924296-17-3
货号 : A637730
分子式 : C16H9N5O
纯度 : 99%+
分子量 : 287.28
MDL号 : MFCD11977747
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 DUB-IN-3, derived from reference compound 22c, is a strong inhibitor of deubiquitinase (USP) enzymes, displaying an IC50 of 0.56 μM for USP8[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.48mL

0.70mL

0.35mL

17.40mL

3.48mL

1.74mL

34.81mL

6.96mL

3.48mL
参考文献

[1]Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8.