ND-646
产品说明书
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同义名 : | - |
| CAS号 : | 1434639-57-2 | |
| 货号 : | A634041 | |
| 分子式 : | C28H32N4O7S | |
| 纯度 : | 99% | |
| 分子量 : | 568.64 | |
| MDL号 : | MFCD30802583 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | ND-646 simultaneously inhibits ACC1 and ACC2, thus preventing ACC2 from compensating for the inhibition of ACC1. ND-646 inhibits the dimerization of the hACC2-BC domain under native conditions. In a cell-free system, ND-646 inhibits the enzymatic activity of hACC1 with an IC50 of 3.5 nM and hACC2 with an IC50 of 4.1 nM[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.76mL 0.35mL 0.18mL |
8.79mL 1.76mL 0.88mL |
17.59mL 3.52mL 1.76mL |
