Poloxin

产品说明书

Print
Chemical Structure| 321688-88-4 同义名 : -
CAS号 : 321688-88-4
货号 : A600407
分子式 : C18H19NO3
纯度 : 98+%
分子量 : 297.35
MDL号 : MFCD20526505
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Poloxin is a non-ATP competitive Polo-like Kinase 1 (PLK1) inhibitor that targets the polo-box domain.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.36mL

0.67mL

0.34mL

16.82mL

3.36mL

1.68mL

33.63mL

6.73mL

3.36mL
参考文献

[1]Yuan J, Sanhaji M, Kr?mer A, Reindl W, Hofmann M, Kreis NN, Zimmer B, Berg T, Strebhardt K. Polo-box domain inhibitor poloxin activates the spindle assembly checkpoint and inhibits tumor growth in vivo. Am J Pathol. 2011 Oct;179(4):2091-9.