AMD 3465

产品说明书

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Chemical Structure| 185991-24-6 同义名 : GENZ-644494
CAS号 : 185991-24-6
货号 : A596316
分子式 : C24H38N6
纯度 : 99%
分子量 : 410.6
MDL号 : MFCD27955785
存储条件：

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 AMD 3465 is a potent, selective CXCR4 antagonist and exhibits 8-fold higher affinity than AMD 3100 and inhibits SDF-1α-ligand binding (Ki = 41.7 nM).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.44mL

0.49mL

0.24mL

12.18mL

2.44mL

1.22mL

24.35mL

4.87mL

2.44mL
参考文献

[1]Ho JD, Xirasagar S, et al. Neovascular age-related macular degeneration is associated with cataract surgery. Acta Ophthalmol. 2017 Jul 3.

[2]Yang L, Jackson E, et al. Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo. Cancer Res. 2007 Jan 15;67(2):651-8.