Amenamevir

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Chemical Structure| 841301-32-4 同义名 : ASP 2151
CAS号 : 841301-32-4
货号 : A588976
分子式 : C24H26N4O5S
纯度 : 99%+
分子量 : 482.55
MDL号 : MFCD19443709
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Amenamevir (ASP2151) inhibits the replication of HSV strains isolated from Japan, the United States, and laboratory-stocked strains. The EC50s of Amenamevir against HSV-1 and HSV-2 are significantly lower than those of acyclovir (ACV) [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.07mL

0.41mL

0.21mL

10.36mL

2.07mL

1.04mL

20.72mL

4.14mL

2.07mL
参考文献

[1]Katsumata K, et al. Pharmacokinetics and pharmacodynamics of ASP2151, a helicase-primase inhibitor, in a murine model of herpes simplex virus infection. Antimicrob Agents Chemother. 2013 Mar;57(3):1339-46.