GW843682X

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Chemical Structure| 660868-91-7 同义名 : GW843682
CAS号 : 660868-91-7
货号 : A582106
分子式 : C22H18F3N3O4S
纯度 : 98%
分子量 : 477.46
MDL号 : MFCD09971143
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 GW843682X is a selective PLK1 and PLK3 inhibitor with IC50s of 2.2 nM (PLK1) and 9.1 nM (PLK3) and displays > 100-fold selectivity over ~30 other kinases tested including cdk1 and cdk2.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.09mL

0.42mL

0.21mL

10.47mL

2.09mL

1.05mL

20.94mL

4.19mL

2.09mL
参考文献

[1]Lansing et al (2007) In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1. Mol.Cancer Ther. 6 450.