同义名 :	δ18-Rynchophylline
	CAS号 :	630-94-4
	货号 :	A571480
	分子式 :	C22H26N2O4
	纯度 :	98+%
	分子量 :	382.45
	MDL号 :	MFCD20527288
	存储条件：	Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation, and is a useful and prospective compound in the prevention and treatment for vascular diseases.

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	2.61mL 0.52mL 0.26mL	13.07mL 2.61mL 1.31mL	26.15mL 5.23mL 2.61mL

参考文献

[1]Wang W, Luo S, et al. Effective Separation and Simultaneous Determination of Corynoxeine and Its Metabolites in Rats by High-Performance Liquid Chromatography with Tandem Mass Spectrometry and Application to Pharmacokinetics and In Vivo Distribution in Main Organs. Anal Sci. 2016;32(6):705-7. [2]Qi W, Chen F,et al. Isolation and identification of twelve metabolites of isocorynoxeine in rat urine and their neuroprotective activities in HT22 cell assay. Planta Med. 2015 Jan;81(1):46-55.