生物活性 | |||
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描述 | AK-1 is a cell permeable, benzylsulfonamide that inhibits SIRT2 activity (IC50= 12.5 µM through enzymatic assay) by targeting the SIRT2 nicotinamide binding site, but may also target SIRT1 and SIRT3 (IC50 >40 µM) with much less potency. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.48mL 0.50mL 0.25mL |
12.39mL 2.48mL 1.24mL |
24.79mL 4.96mL 2.48mL |