Dynole 34-2
产品说明书
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同义名 : | - |
| CAS号 : | 1128165-88-7 | |
| 货号 : | A554857 | |
| 分子式 : | C25H36N4O | |
| 纯度 : | 99%+ | |
| 分子量 : | 408.58 | |
| MDL号 : | MFCD19690957 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Dynole 34-2 is a dynamin GTPase inhibitor with IC50 values of 6.9 and 14.2 µM for dynamin 1 and dynamin 2 GTPase, respectively, and has antimitotic effects. Dynole 34-2 can induce cell apoptosis, manifested by DNA fragmentation and PARP fragmentation[1].Dynole 34-2 also effectively inhibits receptor-mediated endocytosis (RME)[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.45mL 0.49mL 0.24mL |
12.24mL 2.45mL 1.22mL |
24.48mL 4.90mL 2.45mL |
