Kinetin riboside
产品说明书
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同义名 : | 动力精核苷 ;N6-Furfuryladenosine; NSC 120958 |
| CAS号 : | 4338-47-0 | |
| 货号 : | A554446 | |
| 分子式 : | C15H17N5O5 | |
| 纯度 : | 99%+ | |
| 分子量 : | 347.33 | |
| MDL号 : | MFCD00037987 | |
| 存储条件： |
Pure form Keep in dark place, sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Kinetin riboside exhibits activities that hinder cell growth and induce apoptosis in a range of human cancer cell lines. It effectively curbs the proliferation of HCT-15 human colon cancer cells, with the inhibition becoming more pronounced with increasing doses (IC50=2.5 μM)[1]. Kinetin riboside triggers cell death processes in HeLa and B16F-10 melanoma cells. It compromises the mitochondrial membrane integrity, leading to cytochrome c release and caspase-3 activation. The exposure to kinetin riboside results in increased levels of Bad and decreased levels of Bcl-2[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.88mL 0.58mL 0.29mL |
14.40mL 2.88mL 1.44mL |
28.79mL 5.76mL 2.88mL |
| 参考文献 |
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