Setipiprant

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Chemical Structure| 866460-33-5 同义名 : ACT-129968; KYTH-105
CAS号 : 866460-33-5
货号 : A519343
分子式 : C24H19FN2O3
纯度 : 98+%
分子量 : 402.42
MDL号 : MFCD23136043
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Setipiprant is an orally available, selective CRTH2 antagonist.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.48mL

0.50mL

0.25mL

12.42mL

2.48mL

1.24mL

24.85mL

4.97mL

2.48mL
参考文献

[1]Gehin M, Sidharta PN, et al. Pharmacokinetic interactions between simvastatin and setipiprant, a CRTH2 antagonist. Eur J Clin Pharmacol. 2015 Jan;71(1):15-23.

[2]Hoch M, Wank J, et al. Disposition and metabolism of setipiprant, a selective oral CRTH2 antagonist, in humans. Drugs R D. 2013 Dec;13(4):253-69.