E3330

产品说明书

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Chemical Structure| 136164-66-4 同义名 : APX-3330
CAS号 : 136164-66-4
货号 : A510756
分子式 : C21H30O6
纯度 : 98%
分子量 : 378.46
MDL号 : MFCD00901331
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 E3330 is a potent and selective APE1 (Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.64mL

0.53mL

0.26mL

13.21mL

2.64mL

1.32mL

26.42mL

5.28mL

2.64mL
参考文献

[1]Zou GM, Maitra A. Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration. Mol Cancer Ther. 2008 Jul;7(7):2012-21.

[2]Zou GM, Luo MH, et al. Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain. Blood. 2007 Mar 1;109(5):1917-22.