SR9011 HCl

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Chemical Structure| 2070014-94-5 同义名 : -
CAS号 : 2070014-94-5
货号 : A510035
分子式 : C23H32Cl2N4O3S
纯度 : 98%
分子量 : 515.5
MDL号 : N/A
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 SR9011 is the agonist for REV-ERB-α with IC50 of 670 nM and REV-ERB-β with IC50 of 800 nM.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.94mL

0.39mL

0.19mL

9.70mL

1.94mL

0.97mL

19.40mL

3.88mL

1.94mL
参考文献

[1]Wang Y, Kojetin D, et al. Anti-proliferative actions of a synthetic REV-ERBα/β agonist in breast cancer cells. Biochem Pharmacol. 2015 Aug 15;96(4):315-22.

[2]Solt LA, Wang Y, et al. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature. 2012 Mar 29;485(7396):62-8.