Palifosfamide
产品说明书
 |
同义名 : | Isophosphoramide mustard; ZIO-201; NSC 297900; Isophosphamide mustard; IPM |
| CAS号 : | 31645-39-3 | |
| 货号 : | A498867 | |
| 分子式 : | C4H11Cl2N2O2P | |
| 纯度 : | 98+% | |
| 分子量 : | 221.02 | |
| MDL号 : | MFCD01705455 | |
| 存储条件： |
Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Palifosfamide is the functional active metabolite of ifosfamide (IFOS), a bi-functional DNA alkylator being investigated as a potential therapy for the treatment of soft tissue sarcoma (STS). | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02219737 | CD20 Positive ... 展开 >> Recurrent Diffuse Large B-Cell Lymphoma Refractory Diffuse Large B-Cell Lymphoma 收起 << | Phase 1 | Completed | - | United States, New York ... 展开 >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10065 收起 << |
| NCT02441309 | Osteosarcoma | Phase 2 | Completed | - | Germany ... 展开 >> Pediatric Hematology and Oncology, University Hospital Münster Münster, Germany, 48149 Italy Istituti Ortopedici Rizzoli Bologna, Emilia-Romagna, Italy, 40136 Netherlands Department of Clinical Oncology, Leiden University Medical Center Leiden, Postzone K1-P, Netherlands, P.O. Box 9600 Norway Radium Hospital, Oslo University Oslo, Norway, 0310 United Kingdom Leeds Teaching Hospitals NHS Trust Leeds, United Kingdom, LS9 7TF University College London Hospitals NHS Foundation Trust London, United Kingdom, NW1 2BU Christie Hospital NHS Foundation Trust Manchester, United Kingdom, M20 4BX Oxford University Hospitals NHS Foundations Trust Oxford, United Kingdom, OX3 7LE 收起 << |
| NCT00145639 | Osteosarcoma | Phase 2 | Completed | - | United States, Arkansas ... 展开 >> Arkansas Children's Hospital Little Rock, Arkansas, United States, 72202 United States, Missouri Washington University Medical Center St.Louis, Missouri, United States, 63110 United States, Tennessee St.Jude Children's Research Hospital Memphis, Tennessee, United States, 38105 Chile Hospital Luis Calvo Mackenna Santiago, Chile 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
4.52mL 0.90mL 0.45mL |
22.62mL 4.52mL 2.26mL |
45.24mL 9.05mL 4.52mL |
| 参考文献 |
|---|