N-acetylcysteine amide
产品说明书
 |
同义名 : | NACA; N-acetyl-L-Cysteine amide; Nac amide |
| CAS号 : | 38520-57-9 | |
| 货号 : | A497963 | |
| 分子式 : | C5H10N2O2S | |
| 纯度 : | 98% | |
| 分子量 : | 162.21 | |
| MDL号 : | MFCD01696115 | |
| 存储条件： |
Pure form Inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | N-Acetylcysteine amide had no significant effect on the viability of doxorubicin-treated H9c2 cells at less than 1 mM, but produced significant cytotoxicity at 10-20 mM. N-Acetylcysteine amide at a concentration of 750 μM reduced doxorubicin-induced ROS concentration and lipid peroxidation, and restored the GSH/GSSG ratio and the activities of antioxidant enzymes such as catalase (CAT), glutathione peroxidase (GPx), and glutathione reductase (GR)[1].N-Acetylcysteine amide at a concentration of 1 mM protected human brain microvascular endothelial cells (HBMVEC) from methamphetamine-induced cell death[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
6.16mL 1.23mL 0.62mL |
30.82mL 6.16mL 3.08mL |
61.65mL 12.33mL 6.16mL |
