N-acetylcysteine amide

产品说明书

Print
Chemical Structure| 38520-57-9 同义名 : NACA; N-acetyl-L-Cysteine amide; Nac amide
CAS号 : 38520-57-9
货号 : A497963
分子式 : C5H10N2O2S
纯度 : 98%
分子量 : 162.21
MDL号 : MFCD01696115
存储条件:

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 N-Acetylcysteine amide had no significant effect on the viability of doxorubicin-treated H9c2 cells at less than 1 mM, but produced significant cytotoxicity at 10-20 mM. N-Acetylcysteine amide at a concentration of 750 μM reduced doxorubicin-induced ROS concentration and lipid peroxidation, and restored the GSH/GSSG ratio and the activities of antioxidant enzymes such as catalase (CAT), glutathione peroxidase (GPx), and glutathione reductase (GR)[1].N-Acetylcysteine amide at a concentration of 1 mM protected human brain microvascular endothelial cells (HBMVEC) from methamphetamine-induced cell death[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.16mL

1.23mL

0.62mL

30.82mL

6.16mL

3.08mL

61.65mL

12.33mL

6.16mL