7,4'-Di-O-methylapigenin
产品说明书
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同义名 : | 4',7-Dimethoxy-5-Hydroxyflavone; Acacetin 7-methyl ether; Apigenin dimethylether; NSC 94547; 4′-Methoxytectochrysin; 5-Hydroxy-7,4′-dimethoxyflavone; Genkwanin 4′-methyl ether; Dimethoxylapigenin; Apigenin 7,4'-dimethyl ether; 7,4′-Di-O-methylapigenin |
| CAS号 : | 5128-44-9 | |
| 货号 : | A446385 | |
| 分子式 : | C17H14O5 | |
| 纯度 : | 99%+ | |
| 分子量 : | 298.29 | |
| MDL号 : | MFCD00017446 | |
| 存储条件： |
Pure form Inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
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| 描述 | The compound 7,4'-Di-O-methylapigenin may be partly responsible for the reported antifungal activity of C. zeyheri, and may serve as a potential source of lead compounds that can be developed as antifungal phytomedicines.And it also showed inhibition of the drug efflux pumps (with IC50 = 51.64 μg/ml). There was a higher accumulation of ciprofloxacin in Candida cells in the presence of 7,4'-Di-O-methylapigenin than with reserpine. The compound 7,4'-Di-O-methylapigenine demonstrated the activity in a dose-dependent manner with IC50 value of 51.64 μg/ml[3]. In searching for natural products as potential anti-inflammatory agents, 7,4'-Di-O-methylapigenin was not evaluated in vivo for its ability to inhibit acute inflammation[4]. | ||
| 实验方案 | |||
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| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
3.35mL 0.67mL 0.34mL |
16.76mL 3.35mL 1.68mL |
33.52mL 6.70mL 3.35mL |
| 参考文献 |
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