CPI-1189
产品说明书
 |
同义名 : | REN 1654; REN 1189 |
| CAS号 : | 183619-38-7 | |
| 货号 : | A439031 | |
| 分子式 : | C13H18N2O2 | |
| 纯度 : | 97% | |
| 分子量 : | 234.29 | |
| MDL号 : | MFCD00774476 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | CPI-1189, an oral inhibitor of TNF-α release, also impedes the phosphorylation of p38. It has the capability to inhibit apoptosis and is utilized in research related to HIV and neurological diseases[1][2][3][4][5]. CPI-1189, at a concentration of 100 nM and a duration of 1 hour, can effectively prevent oxidative damage and neuronal cell death in SH-SY5Y cells induced by Oxygen glucose deprivation (OGD)/re-oxygenation (OGDR)[3]. CPI-1189, at a concentration of 10 nM and over a period of 2 hours, inhibits the phosphorylation of P38-mitogen-activated protein kinase induced by interleukin1β[4]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
4.27mL 0.85mL 0.43mL |
21.34mL 4.27mL 2.13mL |
42.68mL 8.54mL 4.27mL |
