Guanfacine

产品说明书

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Chemical Structure| 29110-47-2 同义名 : -
CAS号 : 29110-47-2
货号 : A436598
分子式 : C9H9Cl2N3O
纯度 : 98%+
分子量 : 246.09
MDL号 : MFCD00865944
存储条件:

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Guanfacine is a selective α2A receptor agonist.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02204410 Attention Deficit Hyperactivit... 展开 >>y Disorder Deficient Emotional Self-Regulation 收起 << Phase 4 Completed - United States, Massachusetts ... 展开 >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 收起 <<
NCT00684489 Hypertension Not Applicable Completed - -
NCT01172288 Tourettes Syndrome ... 展开 >> Tic 收起 << Phase 2 Completed - United States, Connecticut ... 展开 >> Yale Child Study Center New Haven, Connecticut, United States, 06520 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.06mL

0.81mL

0.41mL

20.32mL

4.06mL

2.03mL

40.64mL

8.13mL

4.06mL

参考文献

[1]Kolar D, Keller A, et al. Treatment of adults with attention-deficit/hyperactivity disorder. Neuropsychiatr Dis Treat. 2008 Apr;4(2):389-403.

[2]Fox H, Sofuoglu M, et al. Guanfacine enhances inhibitory control and attentional shifting in early abstinent cocaine-dependent individuals. J Psychopharmacol. 2015 Mar;29(3):312-23.