Tegobuvir

产品说明书

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Chemical Structure| 1000787-75-6 同义名 : GS-9190; GS 333126; TGV
CAS号 : 1000787-75-6
货号 : A394266
分子式 : C25H14F7N5
纯度 : 99%+
分子量 : 517.4
MDL号 : MFCD18251457
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Tegobuvir is a non-nucleoside nonstructural protein (NS)5B polymerase inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.93mL

0.39mL

0.19mL

9.66mL

1.93mL

0.97mL

19.33mL

3.87mL

1.93mL
参考文献

[1]Vliegen I, Paeshuyse J, et al. In vitro combinations containing Tegobuvir are highly efficient in curing cells from HCV replicon and in delaying/preventing the development of drug resistance. Antiviral Res. 2015 Aug;120:112-21.

[2]Hebner CM, Han B, et al. The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function. PLoS One. 2012;7(6):e39163.