σ1 Receptor antagonist-1
产品说明书
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同义名 : | WQ 1 |
| CAS号 : | 1204401-49-9 | |
| 货号 : | A385332 | |
| 分子式 : | C21H23NOS | |
| 纯度 : | 97% | |
| 分子量 : | 337.48 | |
| MDL号 : | MFCD18206882 | |
| 存储条件： |
Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
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| 靶点 |
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| 描述 | σ1 Receptor antagonist-1 is a potent, selective σ1 receptor antagonist with a pKi value of 10.28. σ1 Receptor antagonist-1 inhibits cell growth, arrests the cell cycle in the G0/G1 phase, and induces apoptosis in MCF-7/ADR cells[1].At a concentration of 10 μM for 48 hours of action, σ1 Receptor antagonist-1 inhibits the growth of MCF-7/ADR cells, arrests the cell cycle in the G0/G1 phase (27.8%) and induces apoptosis[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.96mL 0.59mL 0.30mL |
14.82mL 2.96mL 1.48mL |
29.63mL 5.93mL 2.96mL |
