Propargyl-PEG2-OH

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Chemical Structure| 7218-43-1 同义名 : -
CAS号 : 7218-43-1
货号 : A383690
分子式 : C7H12O3
纯度 : 97%
分子量 : 144.17
MDL号 : MFCD00053353
存储条件：

Pure form Keep in dark place, inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Propargyl-PEG2-OH, a PEG-derived PROTAC linker, is applicable in creating Thalidomide-O-PEG2-propargyl [1]. Propargyl-PEG2-OH, a reagent for click chemistry, possesses an Alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules that have Azide groups.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.94mL

1.39mL

0.69mL

34.68mL

6.94mL

3.47mL

69.36mL

13.87mL

6.94mL
参考文献

[1]Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.