SMIP004

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Chemical Structure| 143360-00-3 同义名 : -
CAS号 : 143360-00-3
货号 : A377805
分子式 : C13H19NO
纯度 : 99%
分子量 : 205.3
MDL号 : MFCD00277686
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 SMIP004 is an inducer of cancer-cell selective apoptosis of human prostate cancer cells, downregulates SKP2 and stabilizes p27.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.87mL

0.97mL

0.49mL

24.35mL

4.87mL

2.44mL

48.71mL

9.74mL

4.87mL
参考文献

[1]Rico-Bautista E, Zhu W, et al. Small molecule-induced mitochondrial disruption directs prostate cancer inhibition via UPR signaling. Oncotarget. 2013 Aug;4(8):1212-29.

[2]Rico-Bautista E, Yang CC, et al. Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cells. BMC Biol. 2010 Dec 23;8:153.