Deferoxamine Mesylate
产品说明书
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同义名 : | 去铁铵 ;Desferrioxamine B mesylate; DFOM; DFX; Deferoxamine (mesylate); DFO; NSC 644468; Desferrioxamine B; Ba 33112 |
| CAS号 : | 138-14-7 | |
| 货号 : | A377160 | |
| 分子式 : | C26H52N6O11S | |
| 纯度 : | 98% | |
| 分子量 : | 656.79 | |
| MDL号 : | MFCD00058605 | |
| 存储条件： |
Pure form Inert atmosphere, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Deferoxamine mesylate as a chelating agent used to remove excess iron from the body, treat acute iron poisoning, especially in small children, used to treat hemochromatosis, that can be either genetic or acquired. It has been previously reported to induce hypoxia and hypoxia-inducible factor-1α (HIF-1α) expression. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT00004982 | Iron Overload ... 展开 >> Thalassemia 收起 << | Phase 1 | Completed | - | United States, New York ... 展开 >> Cornell University Medical College New York, New York, United States, 10021 收起 << |
| NCT00447694 | Beta-thalassemia ... 展开 >> Iron Overload 收起 << | Phase 2 | Completed | - | United States, California ... 展开 >> Childrens Hospital of Los Angeles Los Angeles, California, United States, 90027 Children's Hospital and Research Center at Oakland Oakland, California, United States, 94609 United States, Illinois Children's Memorial Hospital Chicago, Illinois, United States, 60614 收起 << |
| NCT00110266 | Myelodysplastic Syndrome ... 展开 >> Iron Overload 收起 << | Phase 2 | Completed | - | - |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.52mL 0.30mL 0.15mL |
7.61mL 1.52mL 0.76mL |
15.23mL 3.05mL 1.52mL |
| 参考文献 |
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