MPP 2HCl

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Chemical Structure| 911295-24-4 同义名 : MPP dihydrochloride
CAS号 : 911295-24-4
货号 : A369918
分子式 : C29H33Cl2N3O3
纯度 : 99%+
分子量 : 542.5
MDL号 : MFCD06411603
存储条件：

Pure form Inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Selective, high affinity silent antagonist at ERα receptors. Displays > 200-fold selectivity for ERα over ERβ. Ki values are 2.7 and 1800 nM at ERα and ERβ receptors respectively.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT03411525 Health Services Misuse ... 展开 >> Physician's Practice Patterns Guideline Adherence Unnecessary Procedures Health Care Costs 收起 << Not Applicable Recruiting March 1, 2019 United States, Michigan ... 展开 >> IHA Family & Internal Medicine - West Arbor Not yet recruiting Ann Arbor, Michigan, United States, 48103 Contact: Martha Hammond    734-887-4396    martha_hammond@ihacares.com    IHA Internal Medicine - Domino's Farms Not yet recruiting Ann Arbor, Michigan, United States, 48105 Contact: Brett Lamphier    734-995-0303    brett_lamphier@ihacares.com    Michigan Medicine Briarwood Medical Group Not yet recruiting Ann Arbor, Michigan, United States, 48108 Contact: Meghan Moore    734-998-5729    megkatmo@umich.edu    Michigan Medicine East Ann Arbor Health and Geriatrics Center Recruiting Ann Arbor, Michigan, United States, 48109 Contact: Kathie Antieau    734-647-6563    kantieau@umich.edu    University of Michigan Medical School Not yet recruiting Ann Arbor, Michigan, United States, 48109 Contact: Jeffrey T Kullgren, MS, MD, MPH    734-845-3613    jkullgre@umich.edu    Contact: Eve Kerr, MD, MPH    734-845-3504    ekerr@umich.edu    Principal Investigator: Jeffrey T Kullgren, MD, MS, MPH          Sub-Investigator: Jane Forman, ScD, MHS          Principal Investigator: Eve Kerr, MD,MPH          Sub-Investigator: Hyungjin Kim, ScD          Sub-Investigator: Erin Krupka, PhD, MS, MPP          Sub-Investigator: Barbara Soyster, MD          Michigan Medicine Brighton Health Center Not yet recruiting Brighton, Michigan, United States, 48116 Contact: Kristin Lemerand    810-494-2560    kmuzer@umich.edu    IHA Family & Internal Medicine - Cherry Hill Recruiting Canton, Michigan, United States, 48187 Contact: Jody Haney    734-747-6766 ext 18054    martha_hammond@ihacares.com    Michigan Medicine Canton Health Center Not yet recruiting Canton, Michigan, United States, 48187 Contact: Michell Conner    734-844-5391    blancham@med.umich.edu    IHA Internal Medicine - Towsley Not yet recruiting Ypsilanti, Michigan, United States, 48197 Contact: Greg Robinson    734-712-1300    greg_robinson@ihacares.com 收起 <<
NCT02738450 Down Syndrome Phase 1 Recruiting March 2021 United States, Arizona ... 展开 >> St. Joseph's Hospital and Medical Center - Barrow Neurology Clinics Recruiting Phoenix, Arizona, United States, 85013 Contact: Sandy Quintanilla    602-406-7054    Sandy.Quintanilla@DignityHealth.org    Principal Investigator: Anna Burke, MD          United States, California UCSD Adult Down Syndrome Program Recruiting La Jolla, California, United States, 92037-1712 Contact: Asmaa Al-hamdani, M.B.Ch.B, MAS    +1(858) 249 2526    aalhamda@ucsd.edu    Principal Investigator: William Mobley, MD          United States, Maryland Johns Hopkins University Active, not recruiting Baltimore, Maryland, United States, 21224 United States, Massachusetts Massachusetts General Hospital Recruiting Boston, Massachusetts, United States, 02114 Contact: Amy Torres, BS    617-726-7927    aetorres@partners.org    Principal Investigator: Brian Skotko, MD, MPP 收起 <<
NCT02812225 Brain Concussion ... 展开 >> Mild Traumatic Brain Injury 收起 << Not Applicable Recruiting March 2019 United States, Massachusetts ... 展开 >> Beth Israel Deconess Medical Center Emergency Medicine Recruiting Boston, Massachusetts, United States, 02215 Contact: Elinita Rosseto    617-754-2334    erosseto@bidmc.harvard.edu    Contact: Ted Raddell    (617) 754-2334       Principal Investigator: Stephen Epstein, MD, MPP          United States, Ohio University of Cincinnati, Department of Emergency Medicine Recruiting Cincinnati, Ohio, United States, 45267-0769 Contact: Christopher Barczak, MT, CCRP    513-558-8091    christopher.barczak@uc.edu    Contact: Cristina Spinner, CCRP    (513) 558-0698    cristina.spinner@uc.edu    Principal Investigator: Natalie Kreitzer, MD          United States, Tennessee Mountain States Health Alliance Recruiting Johnson City, Tennessee, United States, 37604 Contact: Christy Adkins    423-431-5647    adkinsCE2@msha.com    Contact: Nonna Stepanov, MD    (423) 431-5647    StepanovNV@msha.com    Principal Investigator: Tanzid Shams, MD 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.84mL

0.37mL

0.18mL

9.22mL

1.84mL

0.92mL

18.43mL

3.69mL

1.84mL
参考文献