Inarigivir soproxil

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Chemical Structure| 942123-43-5 同义名 : Sb-9200; GS-9992; SB9200
CAS号 : 942123-43-5
货号 : A359450
分子式 : C25H34N7O13PS
纯度 : 99%+
分子量 : 703.62
MDL号 : MFCD31715418
存储条件：

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 SB-9200 has a broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.42mL

0.28mL

0.14mL

7.11mL

1.42mL

0.71mL

14.21mL

2.84mL

1.42mL
参考文献

[1]Jones M, Cunningham ME, et al. SB 9200, a novel agonist of innate immunity, shows potent antiviral activity against resistant HCV variants. J Med Virol. 2017 Mar 17.

[2]Suresh M, Korolowicz KE, et al. Antiviral Efficacy and Host Immune Response Induction during Sequential Treatment with SB 9200 Followed by Entecavir in Woodchucks. PLoS One. 2017 Jan 5;12(1):e0169631.