IRAK inhibitor 1

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Chemical Structure| 1042224-63-4 同义名 : IRAK4-IN-1
CAS号 : 1042224-63-4
货号 : A356366
分子式 : C17H19N5
纯度 : 99%
分子量 : 293.37
MDL号 : MFCD22124480
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 IRAK inhibitor 1 is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.41mL

0.68mL

0.34mL

17.04mL

3.41mL

1.70mL

34.09mL

6.82mL

3.41mL
参考文献

[1]Buckley GM, Ceska TA, et al. IRAK-4 inhibitors. Part II: a structure-based assessment of imidazo[1,2-a] pyridine binding. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3291-5.

[2]Li S, Strelow A, et al. IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5567-72.