Vesnarinone

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Chemical Structure| 81840-15-5 同义名 : OPC-8212
CAS号 : 81840-15-5
货号 : A354535
分子式 : C22H25N3O4
纯度 : 98+%
分子量 : 395.45
MDL号 : MFCD00867124
存储条件:

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Vesnarinone is a quinolinone derivative, and its pharmacodynamic effects include inhibition of phosphodiesterase III (PDE3) activity, increases in calcium flux and decreases in potassium flux.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT03217955 Psychotic Disorders Not Applicable Completed - -
NCT01494285 Acne Vulgaris Phase 1 Phase 2 Completed - Israel ... 展开 >> HaEmek Medical Center Afula, Israel Meir Medical Center Kfar Saba, Israel Souraski Medical Center Tel Aviv, Israel 收起 <<
NCT03203044 Gut Microbiota Not Applicable Completed - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.53mL

0.51mL

0.25mL

12.64mL

2.53mL

1.26mL

25.29mL

5.06mL

2.53mL

参考文献

[1]Katayama Y, et al. Inhibitory effects of Vesnarinone on cloned cardiac delayed rectifier K(+) channels expressed in a mammalian cell line. J Pharmacol Exp Ther. 2000 Jul;294(1):339-46.