Aripiprazole Lauroxil

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Chemical Structure| 1259305-29-7 同义名 : -
CAS号 : 1259305-29-7
货号 : A333393
分子式 : C36H51Cl2N3O4
纯度 : 99%+
分子量 : 660.71
MDL号 : MFCD26967976
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic. It is an N-acyloxymethyl prodrug of aripiprazole that is administered via intramuscular injection once every four to six weeks for the treatment of schizophrenia.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.51mL

0.30mL

0.15mL

7.57mL

1.51mL

0.76mL

15.14mL

3.03mL

1.51mL
参考文献

[1]Nasrallah HA, Newcomer JW, et al. Effect of Aripiprazole Lauroxil on Metabolic and Endocrine Profiles and Related Safety Considerations Among Patients With Acute Schizophrenia. J Clin Psychiatry. 2016 Nov;77(11):1519-1525.

[2]Rohde M, M Rk N, et al. Biological conversion of aripiprazole lauroxil - An N-acyloxymethyl aripiprazole prodrug. Results Pharma Sci. 2014 May 2;4:19-25.