AI-10-49

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Chemical Structure| 1256094-72-0 同义名 : -
CAS号 : 1256094-72-0
货号 : A332881
分子式 : C30H22F6N6O5
纯度 : 98%
分子量 : 660.52
MDL号 : MFCD28900686
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 AI-10-49 targets the leukemic oncoprotein CBFβ-SMMHC, effectively inhibiting its binding to the RUNX1 Runt domain with an IC50 of 0.26 μM, suggesting its potential for leukemia research[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.51mL

0.30mL

0.15mL

7.57mL

1.51mL

0.76mL

15.14mL

3.03mL

1.51mL
参考文献

[1]Anuradha Illendula, et al. Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice. Science. 2015 Feb 13;347(6223):779-84.