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同义名 : | - |
CAS号 : | 1695533-89-1 | |
货号 : | A321601 | |
分子式 : | C21H17N5O | |
纯度 : | 98+% | |
分子量 : | 355.39 | |
MDL号 : | MFCD31657422 | |
存储条件: |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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溶解度 : | - | |
动物实验配方: |
生物活性 | |||
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描述 | KO-947 is a potent and selective inhibitor of ERK1/2 kinases with potential clinical utility in MAPK pathway dysregulated tumors. |
临床研究 | |||||
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NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT03051035 | Advanced Malignant Neoplasm | Phase 1 | Recruiting | April 15, 2020 | United States, Minnesota ... 展开 >> Mayo Clinic Not yet recruiting Rochester, Minnesota, United States, 55902 United States, Pennsylvania Fox Chase Cancer Center Recruiting Philadelphia, Pennsylvania, United States, 19111-2497 收起 << |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.81mL 0.56mL 0.28mL |
14.07mL 2.81mL 1.41mL |
28.14mL 5.63mL 2.81mL |