FGH10019

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Chemical Structure| 1046045-61-7 同义名 : -
CAS号 : 1046045-61-7
货号 : A321162
分子式 : C18H19N3O2S2
纯度 : 99%
分子量 : 373.49
MDL号 : -
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 FGH10019 is a sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM, displaying 5–10 times lower than the IC50 of fatostatin (~10 μM).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.68mL

0.54mL

0.27mL

13.39mL

2.68mL

1.34mL

26.77mL

5.35mL

2.68mL
参考文献

[1]Kamisuki S, Shirakawa T, et al. Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins. J Med Chem. 2011 Jul 14;54(13):4923-7.