Quiflapon sodium

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Chemical Structure| 147030-01-1 同义名 : Mk-591; MK-591 sodium
CAS号 : 147030-01-1
货号 : A312015
分子式 : C34H34ClN2NaO3S
纯度 : 99%
分子量 : 609.15
MDL号 : MFCD15143438
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 MK591 is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.64mL

0.33mL

0.16mL

8.21mL

1.64mL

0.82mL

16.42mL

3.28mL

1.64mL
参考文献

[1]Sarveswaran S, Myers CE, et al. MK591, a leukotriene biosynthesis inhibitor, induces apoptosis in prostate cancer cells: synergistic action with LY294002, an inhibitor of phosphatidylinositol 3'-kinase. Cancer Lett. 2010 May 28;291(2):167-76.

[2]Mendis C, Campbell K, et al. Effect of 5-lipoxygenase inhibitor MK591 on early molecular and signaling events induced by staphylococcal enterotoxin B in human peripheral blood mononuclear cells. FEBS J. 2008 Jun;275(12):3088-98.