Amitifadine HCl

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Chemical Structure| 410074-74-7 同义名 : DOV-21947 hydrochloride; EB-1010 hydrochloride
CAS号 : 410074-74-7
货号 : A305086
分子式 : C11H12Cl3N
纯度 : 98+%
分子量 : 264.58
MDL号 : -
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Amitifadine hydrochloride is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.78mL

0.76mL

0.38mL

18.90mL

3.78mL

1.89mL

37.80mL

7.56mL

3.78mL
参考文献

[1]Levin ED, Wells C, et al. Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats. Eur J Pharmacol. 2015 Oct 5;764:30-7.

[2]Skolnick P, Popik P, et al. Antidepressant-like actions of DOV 21,947: a "triple" reuptake inhibitor. Eur J Pharmacol. 2003 Feb 14;461(2-3):99-104.