SIRT-IN-3
产品说明书
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同义名 : | - |
| CAS号 : | 1211-19-4 | |
| 货号 : | A303109 | |
| 分子式 : | C13H12N2O | |
| 纯度 : | 97% | |
| 分子量 : | 212.25 | |
| MDL号 : | MFCD00476529 | |
| 存储条件： |
Pure form Keep in dark place,Inert atmosphere,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
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| 描述 | SIRT-IN-3 is a potent inhibitor of SIRT, with an IC50 of 17 μM for SIRT1. It exhibits approximately 4-fold and 14-fold selectivity for SIRT1 over SIRT2 and SIRT3, with IC50 values of 74 μM and 235 μM for SIRT2 and SIRT3, respectively[1]. | ||
| 实验方案 | |||
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| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
4.71mL 0.94mL 0.47mL |
23.56mL 4.71mL 2.36mL |
47.11mL 9.42mL 4.71mL |
| 参考文献 |
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[1]Suzuki T, et al. 2-Anilinobenzamides as SIRT inhibitors. ChemMedChem. 2006 Oct;1(10):1059-62. |