Dicyclanil

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Chemical Structure| 112636-83-6 同义名 : -
CAS号 : 112636-83-6
货号 : A295590
分子式 : C8H10N6
纯度 : 97%
分子量 : 190.21
MDL号 : MFCD03095705
存储条件:

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Dicyclanil is an insect growth regulator compound with a similar chemical structure to cyromazine[1]. The animals of one group in each flock were treated with dicyclanil and those of the other group were left untreated as controls. The trial lasted 31 weeks and the animals were inspected daily for wohlfahrtiosis. When compared with the control groups, dicyclanil achieved a 100 percent reduction of infestation in the treated groups of both flocks for at least 24 weeks, and an 80 percent reduction for 31 weeks[2]. Dicyclanil (5%) provided at least 18 weeks' protection against CYR-LS and DZR50 L. cuprina[3]. Under Australian field conditions, a ready-to-use 5% spray-on formulation of dicyclanil applied off-shears or to long wool protected Merino sheep from blowfly strike for a period of at least 20 weeks[4]. Dicyclanil has neither in vivo genotoxicity nor initiation activity, and suggest that the hepatocarcinogenicity in mice induced by dicyclanil is attributable to a non-genotoxic mechanism[5].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.26mL

1.05mL

0.53mL

26.29mL

5.26mL

2.63mL

52.57mL

10.51mL

5.26mL

参考文献

[1]Sotiraki S, Stefanakis A, Hall MJ, Farkas R, Graf JF. Wohlfahrtiosis in sheep and the role of dicyclanil in its prevention. Vet Parasitol. 2005;131(1-2):107‐117

[2]Sotiraki S, Stefanakis A, Hall MJ, Graf JF. Field trial of the efficacy of dicyclanil for the prevention of wohlfahrtiosis of sheep. Vet Rec. 2005;156(2):37‐40

[3]Baker KE, Rolfe PF, George AJ, Vanhoff KJ, Kluver PF, Bailey JN. Effective control of a suspected cyromazine-resistant strain of Lucilia cuprina using commercial spray-on formulations of cyromazine or dicyclanil. Aust Vet J. 2014;92(10):376‐380

[4]Bowen FL, Fisara P, Junquera P, Keevers DT, Mahoney RH, Schmid HR. Long-lasting prevention against blowfly strike using the insect growth regulator dicyclanil. Aust Vet J. 1999;77(7):454‐460

[5]Moto M, Sasaki YF, Okamura M, et al. Absence of in vivo genotoxicity and liver initiation activity of dicyclanil. J Toxicol Sci. 2003;28(3):173‐179