Eliglustat hemitartrate

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Chemical Structure| 928659-70-5 同义名 : 依利格鲁司特酒石酸盐 ;Eliglustat tartrate; Genz-112638; Eliglustat (hemitartrate); Cerdelga
CAS号 : 928659-70-5
货号 : A295388
分子式 : C50H78N4O14
纯度 : 99%+
分子量 : 959.17
MDL号 : MFCD22665712
存储条件:

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Eliglustat tartrate, a specific inhibitor of glucosylceramide synthase, is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.04mL

0.21mL

0.10mL

5.21mL

1.04mL

0.52mL

10.43mL

2.09mL

1.04mL

参考文献

[1]McEachern KA, Fung J, et al. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy of Gaucher disease. Mol Genet Metab. 2007 Jul;91(3):259-67.