Bufotalin

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Chemical Structure| 471-95-4 同义名 : 蟾毒他灵 ;NSC 89596
CAS号 : 471-95-4
货号 : A287819
分子式 : C26H36O6
纯度 : 98+%
分子量 : 444.56
MDL号 : MFCD00210248
存储条件：

Pure form Inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Bufotalin is a cardiotoxic bufanolide steroid, cardiac glycoside analogue, secreted by a number of toad species and an anti-osteoblastoma agent.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.25mL

0.45mL

0.22mL

11.25mL

2.25mL

1.12mL

22.49mL

4.50mL

2.25mL
参考文献

[1]Zhu YR, Xu Y, et al. Bufotalin-induced apoptosis in osteoblastoma cells is associated with endoplasmic reticulum stress activation. Biochem Biophys Res Commun. 2014 Aug 15;451(1):112-8.

[2]Zhang DM, Liu JS, et al. Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis. Eur J Pharmacol. 2012 Oct 5;692(1-3):19-28.