UNC 0631

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Chemical Structure| 1320288-19-4 同义名 : -
CAS号 : 1320288-19-4
货号 : A284379
分子式 : C37H61N7O2
纯度 : 98%
分子量 : 635.93
MDL号 : MFCD22683862
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 UNC 0631 is a potent inhibitor of histone methyltransferase G9a, with an IC50 of 4 nM. It effectively reduces H3K9me2 levels in MDA-MB-231 cells, with an IC50 of 25 nM [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.57mL

0.31mL

0.16mL

7.86mL

1.57mL

0.79mL

15.73mL

3.15mL

1.57mL
参考文献

[1]Liu F, et al. Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J Med Chem. 2011 Sep 8;54(17):6139-50.