AA26-9

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Chemical Structure| 1312782-34-5 同义名 : -
CAS号 : 1312782-34-5
货号 : A265641
分子式 : C7H10N4O
纯度 : 99%+
分子量 : 166.18
MDL号 : MFCD28386498
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 AA26-9 stands out as a potent and wide-ranging serine hydrolase inhibitor, targeting a diverse array of enzymes within this category, such as serine peptidases, lipases, amidases, esterases, and thioesterases. It exhibits inhibitory effects on about one-third of the more than forty serine hydrolases identified in immortalized T cell lines[1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.02mL

1.20mL

0.60mL

30.09mL

6.02mL

3.01mL

60.18mL

12.04mL

6.02mL
参考文献

[1]Adibekian A, et al. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol. 2011 May 15;7(7):469-78.

[2]Borne AL, et al. Deciphering T Cell Immunometabolism with Activity-Based Protein Profiling. Curr Top Microbiol Immunol. 2019;420:175-210.