BAY 1892005

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Chemical Structure| 2036352-13-1 同义名 : -
CAS号 : 2036352-13-1
货号 : A2630703
分子式 : C11H8ClFN2OS
纯度 : 98%
分子量 : 270.71
MDL号 : N/A
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 BAY 1892005 modulates the p53 protein, targeting p53 aggregates without reactivating mutant p53 forms. BAY 1892005 inhibits the growth of p53 mutant cell lines Huh7 and H358, showing inhibition concentrations (IC50) of 11.2 μM and 11.1 μM, respectively[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.69mL

0.74mL

0.37mL

18.47mL

3.69mL

1.85mL

36.94mL

7.39mL

3.69mL
参考文献

[1]Lemos C, et al. Identification of Small Molecules that Modulate Mutant p53 Condensation[J].iScience, 2020, 23(9):101517.