H-D-Gln-OH
产品说明书
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同义名 : | D-Gln; D-Glutamine |
| CAS号 : | 5959-95-5 | |
| 货号 : | A259333 | |
| 分子式 : | C5H10N2O3 | |
| 纯度 : | 96% | |
| 分子量 : | 146.14 | |
| MDL号 : | MFCD00065607 | |
| 存储条件： |
Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | D-Glutamine is a D-type stereoisomer of glutamine, which is one of the 20 amino acids encoded by the standard genetic code. It has a role as a mouse metabolite and is an enantiomer of L-glutamine. In vivo, when glutamine is administered at a dose higher than 0.35 g/kg/day, it shows the greatest efficacy, and may have the best effect at a dose of 0.5g/kg/day[3]. In vitro, Glutamine plays a protective role through multiple mechanisms, including direct protection of cell and tissue damage, reduction of inflammation, and preservation of metabolic function[4]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT00216970 | Burns | Not Applicable | Unknown | December 2009 | United States, Massachusetts ... 展开 >> MGH Burn Unit Recruiting Boston, Massachusetts, United States, 02114 Contact: Colleen M Sub-Investigator: Colleen M Ryan, MD Sub-Investigator: Shawn P Fagan, MD Sub-Investigator: Robert L Sheridan, MD 收起 << |
| NCT01838915 | HIV | Phase 1 Phase 2 | Active, not recruiting | June 2018 | Spain ... 展开 >> Hospital Ramón y Cajal and Hospital Clínico San Carlos Madrid, Spain, 28034 收起 << |
| NCT01557946 | MDD Citalopra... 展开 >>m Major Depressive Disorder 收起 << | Phase 4 | Completed | - | United States, Massachusetts ... 展开 >> McLean Hospital Belmont, Massachusetts, United States, 02478 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
6.84mL 1.37mL 0.68mL |
34.21mL 6.84mL 3.42mL |
68.43mL 13.69mL 6.84mL |
| 参考文献 |
|---|
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[1]Kim M, Wischmeyer PE. Glutamine. World Rev Nutr Diet. 2013;105:90-6. |