Afzelin

产品说明书

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Chemical Structure| 482-39-3 同义名 : Kaempferol-3-O-rhamnoside; Kaempferol 3-rhamnoside; Kaempferol 3-O-α-L-rhamnopyranoside
CAS号 : 482-39-3
货号 : A257049
分子式 : C21H20O10
纯度 : 99%+
分子量 : 432.38
MDL号 : MFCD00210589
存储条件:

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Afzelin is a natural product isolated and purified from the herbs of thesium chinense Turcz. with s antibacterial activity. Afzelin promotes cytotoxic effect and effectively treats asthma based on reduction of Th2 cytokine via inhibition of GATA‑binding protein 3 transcription factor, which is the master regulator of Th2 cytokine differentiation and production. Afzelin has several cellular activities such as DNA-protective, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protect human skin from UVB-induced damage by a combination of UV-absorbing and cellular activities.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.31mL

0.46mL

0.23mL

11.56mL

2.31mL

1.16mL

23.13mL

4.63mL

2.31mL

参考文献

[1]Jung E, Kim JH, et al. Melanocyte-protective effect of afzelin is mediated by the Nrf2-ARE signalling pathway via GSK-3β inactivation. Exp Dermatol. 2016 Dec 19.

[2]Lee SY, So YJ, et al. Antibacterial effects of afzelin isolated from Cornus macrophylla on Pseudomonas aeruginosa, a leading cause of illness in immunocompromised individuals. Molecules. 2014 Mar 17;19(3):3173-80.