Tricaine methanesulfonate

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Chemical Structure| 886-86-2 同义名 : 3-氨基苯甲酸乙酯甲基磺酸盐 ;MS-222; Ethyl 3-Aminobenzoate (methanesulfonate); NSC 93790; Ethyl m-Aminobenzoate; Ethyl 3-Aminobenzoate methanesulfonate
CAS号 : 886-86-2
货号 : A256653
分子式 : C10H15NO5S
纯度 : 98%
分子量 : 261.29
MDL号 : MFCD00013176
存储条件:

Pure form Sealed in dry,4°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Ethyl 3-Aminobenzoate methanesulfonate is sodium channel blocker often used in anesthesia. To examine whether hypertonicity of myotomes in treated embryos played a role in their shorter rostrocaudal lengths, 1 dpf embryos were exposed to a combination of 25 μM pCPA and 0.6 mM of the sodium channel blocker ethyl 3-aminobenzoate methanesulfonate (MS-222). After a 24 hour exposure, the embryos exhibited the same rostrocaudal length as control embryos suggesting that myotome hypertonicity plays a major role in the decreased axial length of the treated larvae. In addition, pCPA treated 2 dpf embryos exhibited abnormal notochordal morphology that persisted throughout recovery[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.83mL

0.77mL

0.38mL

19.14mL

3.83mL

1.91mL

38.27mL

7.65mL

3.83mL

参考文献

[1]Airhart MJ, Lee DH, Wilson TD, et al. Adverse effects of serotonin depletion in developing zebrafish. Neurotoxicol Teratol. 2012;34(1):152-160