Cardiogenol C

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Chemical Structure| 671225-39-1 同义名 : Cardiogenol C (hydrochloride)
CAS号 : 671225-39-1
货号 : A255739
分子式 : C13H16N4O2
纯度 : 99%+
分子量 : 260.29
MDL号 : MFCD09037525
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Cardiogenol C, a powerful and cell-permeable pyrimidine inducer, triggers the differentiation of ESCs into cardiomyocytes with an EC50 of 100 nM[1]. Cardiogenol C induces cardiomyogenesis in lineage-committed progenitor cells possessing limited plasticity. It serves as an effective cardiomyogenic agent, potentially enhancing cardiac repair through cell transplantation therapy in animal models[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.84mL

0.77mL

0.38mL

19.21mL

3.84mL

1.92mL

38.42mL

7.68mL

3.84mL
参考文献

[1]Wu X, et al. Small molecules that induce cardiomyogenesis in embryonic stem cells.J Am Chem Soc. 2004 Feb 18;126(6):1590-1.

[2]Mike AK, et al. Small molecule cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells. Cell Physiol Biochem. 2014;33(1):205-21.