MnTBAP

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Chemical Structure| 55266-18-7 同义名 : MnTBAP chloride; Mn(III)TBAP (chloride)
CAS号 : 55266-18-7
货号 : A241977
分子式 : C48H28ClMnN4O8
纯度 : 98%+
分子量 : 879.15
MDL号 : MFCD06227760
存储条件:

Pure form Sealed in dry,Store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 MnTBAP chloride acts as a superoxide dismutase (SOD) mimic and peroxynitrite scavenger. It is a manganic porphyrin complex with antioxidative properties. MnTBAP chloride exerts anti-inflammatory actions by upregulating BMPR-II and suppressing NFκB signaling. It has the potential for research into fibrotic responses in chronic kidney diseases (CKDs)[1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.14mL

0.23mL

0.11mL

5.69mL

1.14mL

0.57mL

11.37mL

2.27mL

1.14mL

参考文献

[1]Jing Yu, et al. MnTBAP Therapy Attenuates Renal Fibrosis in Mice With 5/6 Nephrectomy. Oxid Med Cell Longev. 2016;2016:7496930.

[2]Qian Zhou, et al. MnTBAP Increases BMPR-II Expression in Endothelial Cells and Attenuates Vascular Inflammation. Vascul Pharmacol. 2016 Sep;84:67-73.