Magmas-IN-1

产品说明书

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Chemical Structure| 1251957-89-7 同义名 : -
CAS号 : 1251957-89-7
货号 : A2417383
分子式 : C20H27N3O
纯度 : 98%
分子量 : 325.45
MDL号 : MFCD34604007
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Magmas-IN-1, a small molecule, acts as a Magmas inhibitor (SMMI), targeting a mitochondria-associated granulocyte-macrophage colony-stimulating factor signaling molecule and a GM-CSF inducible gene in myeloid cells. It impacts mitochondrial functionality and restricts yeast proliferation at 4 μM[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.07mL

0.61mL

0.31mL

15.36mL

3.07mL

1.54mL

30.73mL

6.15mL

3.07mL
参考文献

[1]Jubinsky PT, et al. Design, synthesis, and biological activity of novel Magmas inhibitors. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3479-82.