COX-2-IN-32

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Chemical Structure| 2725863-08-9 同义名 : -
CAS号 : 2725863-08-9
货号 : A2288276
分子式 : C25H24O6
纯度 : 99%+
分子量 : 420.45
MDL号 : N/A
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 COX-2-IN-32 inhibits both iNOS and COX-2, leading to reduced NF-κB expression and showcasing anti-inflammatory effects by lowering NO levels in LPS-stimulated RAW264.7 macrophages (IC50: 11.2 μM)[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.38mL

0.48mL

0.24mL

11.89mL

2.38mL

1.19mL

23.78mL

4.76mL

2.38mL
参考文献

[1]Emam SH, et al. Design and synthesis of methoxyphenyl- and coumarin-based chalcone derivatives as anti-inflammatory agents by inhibition of NO production and down-regulation of NF-κB in LPS-induced RAW264.7 macrophage cells. Bioorg Chem. 2021 Feb;107:104630.